Wild card Svetlana Kuznetsova, the former World No.2 and a two-time Grand Slam champion, will meet Swiss qualifier Jil Teichmann for the first time. Kuznetsova’s best result in Prague is a semifinal run in 2016.
Katerina Siniakova takes a 3-0 head-to-head lead into her encounter with Slovakian wild card Jana Cepelova. Their last match came at Tokyo in 2017, which Siniakova won in three sets. Siniakova has a 9-4 career win-loss record in Prague, reaching the quarterfinals in the last two years and the semifinals in 2015.
Barbora Strycova also has a solid 8-4 record in Prague, with a semifinal showing in 2017 and back-to-back quarterfinals in 2015 and 2016. Strycova will take on Jessica Pegula for the first time.
This will be the first professional meeting between Russians Natalia Vikhlyantseva and Anastasia Potapova. 18-year-old Potapova, the youngest player to receive direct entry into the main draw, experienced a breakthrough year in 2018, reaching two WTA singles finals (Moscow and Tashkent) and bursting into the Top 100 for the first time.
World No.16 Wang Qiang is the highest-ranked player remaining in the draw. The No.3 seed has now made the second round at Prague for three straight years but is trying to make it to the quarterfinals for the first time. She has lost her only prior match with Mandy Minella, which came in Baku in 2012.