The No. 18 Colorado Buffaloes and the Southern California Trojans are set to square off in a Pac-12 matchup at 9 p.m. ET Thursday at CU Events Center. The Buffaloes are 20-6 overall and 12-2 at home, while USC is 19-7 overall and 5-4 on the road. Colorado has won four of its past five games. USC is aiming for a third consecutive win. The Buffaloes are favored by 9.5 points in the latest Colorado vs. Southern California odds, while the over-under is set at 135.5. Before entering any USC vs. Colorado picks, you’ll want to see the college basketball predictions from the model at SportsLine.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. It also entered Week 16 of the 2019-20 season on a 54-30 run on all top-rated college basketball picks. Anybody who followed it has seen huge returns.

Now, the model has set its sights on Colorado vs. Southern California. You can head to SportsLine to see its picks. Here are several college basketball odds for USC vs. Colorado:

• Colorado vs. Southern California spread: Colorado -9.5
• Colorado vs. Southern California over-under: 136 points
• Colorado vs. Southern California money line: Colorado -512, Southern California 380

What you need to know about Colorado

Colorado took its contest against the Oregon State Beavers on Saturday by a conclusive 69-47 score. Tyler Bey posted a double-double on 21 points and 15 boards, and McKinley Wright IV also had a double-double on 13 points and 10 rebounds in addition to six dimes. The Buffaloes moved into sole possession of first place in the Pac-12 with the victory. Colorado led by as many as 24 points. 

Colorado rolled past USC in the last meeting between the teams on February 1, 78-57. 

What you need to know about USC

The matchup between USC and the Washington State Cougars on Saturday was a pretty decisive one as USC scored a 70-51 win at home. Daniel Utomi shot 5-for-10 from beyond the arc and finished with 23 points and six rebounds. It was the lowest scoring game for a USC opponent in Pac-12 play this season.

Onyeka Okongwu has missed the past two games because of a concussion, but is expected to return on Thursday.

How to make USC vs. Colorado picks

SportsLine’s model has simulated Colorado vs. USC 10,000 times and the results are in. It is leaning under on the total, and it’s also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Colorado vs. USC? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to find out which side of the Southern California vs. Colorado spread you need to jump on Thursday, all from the model that has crushed its college basketball picks.